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Glossary of Terms
 

UNDERSTANDING TODAY’S PHARMACY

COST CONTAINMENT STRATEGIES

 
Exhibit B.1 DP/Rx 11/9/99
     Fraud, Abuse and Waste were the conditions that best described the primary sources of excessive costs in pharmaceutical benefit programs prior to 1985. Fraud was virtually eliminated in the USA when the real-time POS computer systems commenced operations in 1985. Losses were estimated to be as large as 20% of total expenditures at that time. Intercepting fraudulent prescriptions before dispensing was the key to this major cost reduction. This savings area remains a potential saving for South American countries because of the absence of POS (Point of Sale) systems.
 
     Further inroads were made in the USA, after eliminating the fraud problem, to reduce excessive costs by intercepting other inappropriate conditions prior to dispensing at the POS. These dispensing intercepts reduced large amounts of Abuse and Waste. The early 1990s introduced some strategies to influence lower costs in addition to employing programmed limits to curtail excessive utilization by eligible members of benefit plans. There may another 20%-25% unnecessarily spent due to Waste and Abuse.
 
    After successfully solving the Fraud Abuse and Waste excesses, drug benefit planning then added another savings area to their list of goals to achieve. The benefit administrator then looked to substituting inexpensive comparable drugs for the more expensive drugs. Typically, Brand drugs are far more expensive than Generic drugs. Surveys indicate that using an average cost for Brands of $35 per Rx and $8 for Generics is reasonable for projecting the impact of generic strategies.
 
     Today’s popular strategies and controls to reduce costs are listed below in their approximate order of greatest savings impact:
 
     GENERIC INCENTIVES. Mandatory generic substitution can be employed but many benefit managers are cautious about using inflexible approach. Since the difference between generic and brand costs is so great it is desirable to provide an incentive to create more than a 50% voluntary substitution rate. Brands average over $35 per Rx while generics average below $10 per Rx. If the plan is designed to impose a high co-pay against the co-pay for the equivalent generic, one can expect a considerable voluntary acceptance of the lower co-pay. For instance, a co-pay of 50% of the ingredient cost for brands and a 20% co-pay for generics results in a $17.50 versus $2.00 decision for the buyer’s choice. In this case, the benefit sponsor saves $9.50 or over 50% of the brand cost. This scheme is operative in an "open" formulary.
 
Lives = 1,000,000 100% Brands 50% Brands 100% Generics
Cost of Brands @ $35 $227,500,000 100% $113,750,000 50% $0 0%
Cost of Generics @ $10 $0 $32,500,000 14% $65,000,000 28%
 
     By the annualized table shown above, it can be seen that a complete conversion to generics may reduce costs 72%. A 50% conversion to Generics results in an estimated reduction in costs of 36%.
 
     CLOSED FORMULARY (EXCLUSIONS). Formularies are lists of drugs grouped by therapeutic classification so that a substitution of a therapeutically equivalent drug can be made from that list. The purpose is to substitute a lower cost drug, which results in a lower cost for the benefit sponsor. This list can be constructed with more expensive brands omitted. The plan can be constructed require a selection from the abridged Formulary as mandatory. This is called a "closed" formulary. In this strategy, the member/patient is not provided any choices unless a specific over-ride is performed by the administrator. This approach is not universally used because of the no-option mandate. The "open" formulary is not a mandatory dispensing list and it is ordinarily used to apply incentives (for Generics) or disincentives (for Brands) based on the drug selected. The 100% Generics figures given in the table above are applicable based on the use of a closed formulary that excludes all Brands.
 
     DEDUCTIBLES. This is a form of cost sharing that is not universally used by benefit managers. It is the equivalent of 100% co-pay (member pays entire cost) until a designated minimum cumulative dollar amount is reached in out-of-pocket expense by the patient. If the deductible, usually an annual amount, is chosen wisely the effect on total cost is substantial. The lowest utilizing members are more adversely effected and this approach results in the disaffection of the group more desirable to the sponsor.
 
     The impact of two different deductibles is used for two scenarios. The first is for an average population using 7 Rx’s per year and the second is for a typical older population using an average of 15 Rx’s per year. The dollar figures calculated is for a 1 million lives group and for using only Brand drugs with no co-pay. The savings are a substantial 61% and 82% for the normal group using a deductible of $100 and $200, respectively. The older group, as you would expect has a lower impact which indicates that a higher deductible should be chosen for greater savings.
 
     MAXIMUMS. This approach is one that triggers a 100% co-pay when the patient-member’s utilization reaches an aggregate dollar maximum amount. This maximum can be applied annually or for a lifetime. It has the more desirable effect of affecting the highest utilizers. It also has the benefit of limiting total exposure of the benefit sponsor. Like deductibles, this strategy is not universally used by benefit administrators.
 
Lives = 1,000,000 No Maximum $200 Maximum $300 Maximum
7 Rxs/yr, Brands @$35 $245,000,000 100% $200,000,000 82% $245,000,000 100%
15 Rxs/yr, Brands @$35 $525,000,000 100% $200,000,000 38% $450,000,000 86%
 
     The impact of two different Maximum amounts for two different groups is used in the table above. No co-pays are used in this example but the effect on the curtailment of costs is illustrated in degree. This strategy is most beneficial for high utilizing groups such as populations whose ages are all over 50 years. The lower the maximum amount, the greater the impact. The $200 annual maximum for the old group would probably be difficult to sell to the group if there was no relief in prices because of the Brand intensity. A Maximum strategy combined with the Generic Incentive strategy could probably provide an acceptable plan for the older population since very few members’ aggregate-usage would rise to either maximum ($200 or $300) if Generics were accepted for the majority of drugs dispensed.
 
     REFILL-TOO-SOON. This is less a strategy than it is a control mechanism. It is used to prevent over utilization of drugs beyond the designated rate of consumption ("dosage") ordered by the physician. A maximum days-supply of the drug is arbitrarily selected and additional dispensing is allowed by the "refill". Thirty (30) days-supply is the most widely-used maximum quantity. The POS intercept will deny a refill when the patient requests one in less than the designated maximum duration. The TeleCLAIM system uses a parameter for flexible treatment of the rule by allowing a percentage reduction in the maximum duration. The system also accommodates a variance from the rule if authorized by an "over-ride" option.
 
Lives = 1,000,000 30 days average refill 25 days average refill 20 days average refill
100% Maint. @$35/Rx $420,000,000 100% $511,000,000 122% $639,000,000 152%
50% Maint. @$35/Rx $420,000,000 100% $466,000,000 111% $530,000,000 126%
 
     One of the more costly abuses is usually over utilization of drugs unless the POS system is directed to intercept and limit abuse of this kind. Without such controls, experience has shown that patients tend to increase their usage with maintenance therapies rather than reduce use. The figures in the table above give a sense of how expensive this abuse would be if not intercepted by the POS system. Some plans will dispense when intercepting such abuse and add a penalty to deter the abuser. The majority of administrators prevent dispensing unless the patient provides a means of securing an over-ride (PAR – Prior Authorization) by the Pharmacist. These administrators; however, will allow some latitude by a few days early to placate those that can not get a refill on exactly the 30th day.
 
     MAINTENANCE DRUGS BY MAIL ORDER. Chronic disorders ordinarily are treated with drug therapies that may create a continuing stream of refills. Oftentimes considerable savings can be achieved by dispensing larger quantities of the drug that results in a much longer duration. (e.g. – 90 days-supply instead of 30 days-supply). This is a strategy that saves money in the USA because it eliminates the multiple dispensing fees of the pharmacy. While dispensing fees are non-existent in the South American community due to packaged dispensing, there may be a savings to the sponsor because of the elimination of the pharmacist’s larger profit. Mail order facilities can provide lower prices for drugs due to high volume purchases and the mechanized methods of filling drug orders with non-pharmacist, lower cost personnel. The cost of delivery in these circumstances must be significantly lower than the savings attained by lower prices and lower-cost labor as described. This is a popular strategy for an older population of members who are more likely to have greater utilization patterns and chronic disorder drug therapies.
 
     OTHER CONTROLS. There are a number of other control features that are employed by administrators. One that accounts for a significant reduction in excess expenditures is the Duplicate Therapy intercept. In this case the system checks the therapeutic intent of a prescribed drug against others in use by the patient. When they are identical in therapeutic capability, the new drug is denied. The prescriber may have been a different prescriber from the original drug and possibly intended the drug for a different purpose. In that case the prescribers may collaborate and decide on another more universal drug to treat both problems.
 
     DUR (Drug Utilization Review) analyzes a number of issues that, absent investigation, may contribute to abuse and waste. These include Dosage Check (high/low levels), gender mismatches, age dispensing disparities, and others. Problems with these issues exist but are not major in cost terms when compared to the issues described above but are still worthy of scrutiny and intercept.
 
SUMMARY.
 
     Without POS systems, as is the case in South America, where ever there exists a pharmacy benefit program there is likely to be as much as 50% savings possible. We know by experience that Fraud alone can account for 20% excessive expense. Major elements of Abuse and Waste can account for another 10 to 20%. These items alone are easily eliminated with the POS solution.
 
     After these items are cured, then there are further reductions possible by various strategies that are easily implemented. Generic substitution, of course, can have the greatest impact for great savings. The preponderance of benefit plans use incentives or penalties, rather than outright banning of more expensive drugs, to influence selection of Generics by the patient member. A conversion of even 10% has a dramatic savings effect due the large differential between Brands and Generic (e.g. - $35 vs. $10).
 
     Clearly the use of formularies sets the basis for using exclusions of certain drugs and equipment that are questionable as means of curing disease and disorders. Such peripheral products would include OTC drugs, weight reduction drugs, smoking abatement aides, birth control drugs, beauty aides and many other similar purpose drugs.
 
     Deductibles and maximum limiting controls are also strategies and tools that can have a substantial effect on reducing costs. These used cautiously due to the negative impact it can have on the most needy of medical patients. Marketing professionals will testify to the difficulty of selling these premium reducing techniques.
 
     It is the opinion of DP/Rx that savings of great amounts are possible when employing fundamental and sophisticated tools and techniques already proven effective in the USA market.
 
 

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